Successful Treatment of Brainstem Blastomycosis with Fluconazole

  • August 2011,
  • cmr.2011.1023;
  • DOI: https://doi.org/10.3121/cmr.2011.1023

Abstract

Lipid formulation of amphotericin B is the initial drug of choice for central nervous system blastomycosis, but it is costly and associated with significant toxicity. This case report details a patient with primary pulmonary blastomycosis with dissemination to skin, joint, and brainstem that was successfully treated solely with high-dose fluconazole.

  • Received May 17, 2011.
  • Revision received June 21, 2011.
  • Accepted July 6, 2011.
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