Treatment-Refractory Mania with Psychosis in a Post-Transplant Patient on Tacrolimus: A Case Report

  • Clinical Medicine & Research
  • May 2018,
  • cmr.2018.1409;
  • DOI: https://doi.org/10.3121/cmr.2018.1409

Abstract

Bipolar affective disorder type I imparts significant morbidity and disease burden in the Population. It is characterized by occurrence of one or more manic episodes which may be preceded or followed by a depressive or hypomanic phase. About half of these manic episodes are characterized by the presence of psychotic features [1]. The condition is further complicated when patient has multiple comorbid conditions. We report here a case of a 66 year old Caucasian female, previously diagnosed with Bipolar disorder who developed treatment refractory mania with psychotic feature after being on Tacrolimus (an immunosuppressive agent) after kidney transplantation.

  • Received December 21, 2017.
  • Revision received April 13, 2018.
  • Accepted May 1, 2018.
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