Reduced Maladaptive Behavior and Improved Social and Communicative Function in a Child with Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS) Treated with Progesterone

Abstract

This case report presents the use of progesterone for the regulation of an atypical menstrual cycle in an 11-year-old girl who is also diagnosed with Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS). The progesterone (150mg) injections alleviated the prolonged, heavy monthly blood flow, but also caused significant changes for the better in the patient’s mood, behavior, and cognition within four weeks following the injections. The use of hormonal treatments, such as progesterone, to effect mood, behavior, and cognition should be further researched to determine other potential therapeutic uses.