Abstract
Sarcoidosis is a chronic inflammatory multisystem disease of unknown etiology. We report on a 57-year-old woman presenting with typical sarcoidosis occurring two months after completion of a six-month course of interferon-α (IFN-α) and ribavirin for chronic hepatitis C virus (CHC) infection. The current observation is interesting with regard to the time elapsed between symptoms occurrence and antiviral treatment withdrawal and spontaneous recovery after ten months of follow-up. Pathophysiological mechanisms involved in the development of antiviral therapy-induced sarcoidosis are discussed in the present article.
- Chronic hepatitis C
- Interferon-alpha and ribavirin combination therapy
- Sarcoidosis
- Spontaneous recovery
- Received September 14, 2009.
- Revision received February 5, 2010.
- Accepted February 10, 2010.
