Cover image

ON THE COVER:

Human papilloma viruses. Computer artwork of human papilloma virus (HPV) virions (particles). This virus consists of a protein capsid enclosing DNA (deoxyribonucleic acid), the virus' genetic material. Attached to the capsid are numerous surface proteins (spikes). HPV causes warts, which mostly occur on the hands and feet. Certain strains also infect the genitals. Although most warts are non-malignant (non-cancerous) some strains of HPV have been associated with cancers, especially cervical cancer.

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See related article:

"Human Papillomavirus Infections in Primary Care" pp. 210–217

In this issue of Clinical Medicine & Research, Ogunmodede et al provide an overview of the treatment approach for genital warts and management of abnormal cervical cytology based on guidelines from the American Society of Colposcopy and Cervical Pathology. The authors also review advances in HPV vaccine development and the recombinant vaccine recently approved for use in the United States.