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ON THE COVER:

Alzheimer disease. Conceptual artwork of a brain and nerve cells to depict dementia due to Alzheimer disease. A sagittal slice through the brain is overlain with nerve cells. The nerve cells (neurons) have long axons and dendrites and cell bodies (triangular-shaped). At bottom the image of a face is repeated on a staircase, getting smaller as the staircase gets higher. Dementia is a general decline in mental ability and progressively gets worse. The most common cause of dementia is Alzheimer disease in which the brain’s nerve cells degenerate and the size of the brain substance shrinks.

Image by H-U Osterwalder. Image and text copyright 2007 Photo Researchers, Inc. All Rights Reserved. Licensed from Photo Researchers, Inc. for reproduction by Clinical Medicine & Research.

See related article: "The Contribution of Luteinizing Hormone to Alzheimer Disease Pathogenesis" pp. 177-183. pp. 177–183.

In this issue of Clinical Medicine & Research, Webber et al review the evidence for the role luteinizing hormone plays in the development and progression of Alzheimer Disease.