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ON THE COVER: See related article: Genotyping Parkinson Disease-Associated Mitochondrial Polymorphisms pp. 99–106. Mitochondria within human cells fluoresce red when stained with the probe MitoTracker Red CMXRos (Molecular Probes, Eugene, Oregon). The mitochondrial morphology can switch between the familiar ovoid-shape to a single branched structure depending on the stage of the cell cycle. In this issue of Clinical Medicine & Research, Jiang et al. describe a rapid method for identifying single nucleotide polymorphisms that define mitochondrial DNA haplogroups using mitochondria isolated from human blood. Photo courtesy of Tamara A. Kronenwetter-Koepel, Marshfield Clinic Research Foundation. (C)2004 Clinical Medicine & Research