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ON THE COVER: See related article: Monkeypox, Marshfield Clinic, and the Internet: Leveraging Information Technology for Public Health pp. 1–3> A negative stain electron micrograph reveals a "M" (mulberry type) monkeypox virus virion in human vesicular fluid. The surface of "M", or "mulberry" virions are covered with short, whorled filaments, while "C", or "capular" form virions penetrated by stain present as a sharply defined, dense core surrounded by several laminated zones of differing densities. In this issue of Clinical Medicine & Research, Dr. Kurt Reed gives a perspective on leveraging information technology for public health as demonstrated during the 2003 Monkeypox outbreak. Content Provider(s): CDC/Charles D. Humphrey, Tiara Morehead, and Russell Regnery. Image courtesy of the CDC Public Health Image Library