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ON THE COVER: See related article: Neurologic Conditions: Assessing Medical Fitness to Drive pp. 177–188 Clinicians are often asked to make an assessment on whether a patient is medically fit to drive, even though few have been formally trained in this area. Driving is a complex task that requires having adequate operational, cognitive and higher executive functions that work together. These functions can be compromised to a greater or lesser extent in neurological disorders, such as stroke, traumatic brain injury, peripheral neuropathy, dementia, Parkinson's disease and epilepsy. These and other factors, as well as practical recommendations for the practicing physicians, are the subjects of this review.