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ON THE COVER:
"Influenza virus particles."
Computer artwork of influenza (flu) virus
particles with people in the background.
Each particle comprises a core (central
sphere) surrounded by membranes. The
outer membrane bears the proteins
neuraminidase and hemagglutinin (spikes),
which help the virus to enter a host cell. The
virus uses its host cell's genetic machinery
to produce more copies of itself. These copies
make a new outer membrane and erupt from the
cell to infect others. The influenza virus is a
type of orthomyxovirus. It cause fever,
weakness and aching muscles.
Image and text reproduced with permission. Copyright 2003 Photo Researchers, Inc., New York, NY. All rights reserved.
See related article: Efficacy of the Influenza Vaccine in Patients with Malignant Lymphoma. pp. 214-220
In this issue of Clinical Medicine & Research,
Mazza et al. describe a clinical study of the
efficacy of the influenza vaccine in
immunosuppressed patients. Patients with
malignant lymphoma (Hodgkin's and Non-Hodgkin's lymphoma) and who were
receiving chemotherapy during the 2003
influenza season were eligible to participate.
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