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Systemic Blastomycosis Diagnosed by Prostate Needle Biopsy

Peter M. Neal, MD, Department of Urology, Marshfield Clinic Indianhead Center, 1020 Lakeshore Drive, Rice Lake, Wisconsin 54868
Anne Nikolai, BS, Clinical Research Center, Marshfield Clinic Research Foundation, 1000 North Oak Avenue, Marshfield, Wisconsin 54449

Reprint Requests: Peter M. Neal, MD, Department of Urology, Marshfield Clinic Indianhead Center, 1020 Lakeshore Drive, Rice Lake, WI 54868, Tel: 715-236-8313, Fax: 715-236-8104, Email: neal.peter{at}marshfieldclinic.org

A healthy 51-year-old man presented with a 1-month history of lower urinary tract irritative symptoms. Urinalysis was suggestive of infection, and the patient was treated with multiple antibiotics without relief of symptoms.A urological exam demonstrated abnormal induration of the prostate gland. Biopsy of the prostate gland revealed Blastomyces dermatitidis. In areas where Blastomyces dermatitidis is endemic, clinicians should be aware of the presence of this fungus and possible sites of infection.

Key Words: Blastomycosis • Blastomyces dermatitidis • Endemic disease • Genitourinary blastomycosis • Mycotic disease, prostatic diagnosis • Prostatic blastomycosis