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Clinical Medicine & Research
Volume 3, Number 2 : 109
doi:
© 2005 Marshfield Clinic
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The Aperture

Diagnosis?

Christopher J. Cold, MD, Thomas L. Sell, MD and Kurt D. Reed, MD

Marshfield Clinic, Marshfield,Wisconsin

Abstract

A female, 62 years of age, was hospitalized with respiratory failure, mental status changes, and profound muscle weakness. She had been treated recently with methotrexate and steroids for pseudo-tumor cerebri and sero-negative arthritis. A CT scan of the head revealed multiple small enhancing lesions. The photos shown here include a hematoxylin and eosin stained section and transmission electron microscopy of the patient’s muscle biopsy.

Key Words: Biopsy • Muscles • Pseudotumor cerebri • Arthritis • Muscle weakness • Respiratory insufficiency • X-ray computed tomography • Transmission electron microscopy






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